Forkhead box protein M1 is a protein that in humans is encoded by the FOXM1 gene. The protein encoded by this gene is a member of the FOX family of transcription factors. Its potential as a target for future cancer treatments led to it being designated the 2010 Molecule of the Year. See more FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases. FOXM1-null mouse embryos were neonatal lethal as a result of the development of See more FOXM1 gene is now known as a human proto-oncogene. Abnormal upregulation of FOXM1 is involved in the oncogenesis of basal cell carcinoma, … See more The exact mechanism of FOXM1 in cancer formation remains unknown. It is thought that upregulation of FOXM1 promotes oncogenesis through abnormal impact on its multiple roles in cell cycle and chromosomal/genomic maintenance. Aberrant … See more FOXM1 has been shown to interact with Cdh1. See more There are three FOXM1 isoforms in humans, A, B and C. Isoform FOXM1A has been shown to be a gene transcriptional See more A recent report by the research group which first found that the over-expression of FOXM1 is associated with human cancer, showed … See more Given the role in progenitor/stem cells expansion, FOXM1 has been shown to modulate the epigenome. It was found that overexpression of FOXM1 "brain washes" normal cells to … See more
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WebApr 9, 2024 · forkhead box protein M1, Forkhead, drosophila, homolog-like 16, HNF-3/fork-head homolog 11, M-phase phosphoprotein 2, MPM-2 reactive phosphoprotein 2, forkhead box M1-D, forkhead-related protein FKHL16, hepatocyte nuclear factor 3 forkhead homolog 11, transcription factor Trident, winged-helix factor from INS-1 cells. http://etds.lib.ncku.edu.tw/etdservice/detail?n=20&etdun3=U0026-0807201015382600&etdun4=U0026-0308201013054000&etdun7=U0026-0507201015382300&etdun9=U0026-0812200915245712&etdun10=U0026-0812200915112049&etdun11=U0026-0812200915225650&etdun12=U0026-0812200915235022&etdun18=U0026-0812200915161691&etdun19=U0026-0812200915163317&etdun20=U0026-0812200915165141 importance of continentality
Novel Compound May Block Certain Forms of Aggressive Cancer
WebJun 19, 2024 · Forkhead box M1 (FOXM1) is a member of the conserved forkhead box (FOX) transcription factor family. Over the last two decades, FOXM1 has emerged as a … WebThe Journal of Clinical Investigation期刊最新论文,,顶级期刊最新论文图文内容,出版社网站每日同步更新,点击标题直达论文原文,自定义关注的期刊,覆盖PubMed的论文库,快速方便精准的找到您想要的论文 WebDec 18, 2024 · The hard hat features a milwaukee®. Hard hat pencil holder adhesive clip tool with tons of uses 3 pack black 3 count (pack of 1) 541 $825 ($2.75/count) free … importance of consumers in economy