WebDec 12, 2015 · Exome sequencing initially revealed a conserved mutation in the gene encoding ribosomal protein L10 (also known as uL16 32) in ∼10% of T-cell acute lymphoblastic leukemias 33, and followup studies revealed that this mutation promotes globally increased rates of -1 PRF 34, 35. WebEukaryotic rpL10 drives ribosome rotation Article Full-text available Nov 2013 NUCLEIC ACIDS RES Sergey O Sulima Suna P Gülay Margarida Anjos Stephanie Patchett Jonathan D Dinman Ribosomes...
Structural basis for the transition from translation ... - Nature
Web(2014) Sulima et al. Nucleic Acids Research. Ribosomes transit between two conformational states, non-rotated and rotated, through the elongation cycle. Here, we present evidence … WebOct 15, 2024 · Eukaryotic large ribosomal subunit and RPL10 mutations. Tetrahymena termophila 60S subunit, views of the 40S-exposed (A) and solvent-exposed (B) sides. … life hacks for colleges
Eukaryotic rpL10 drives ribosomal rotation. BioGRID
WebMar 31, 2014 · As revealed by extensive rRNA chemical modification analyses, the internal loop of rpL10 is a central driver of ribosomal rotation . In the current study, analysis of … WebFigure 7. Involvement of the rpL10 loop in ribosome rotation throughout the ribosomal life cycle. (a) The elongation cycle of translation: rpL10 loop positioning and ligand binding. The elongation cycle begins at left with the ribosome in the non-rotated state where the E-site contains a deacylated tRNA, the P-site is occupied by peptidyl tRNA, and the un … WebMolecular Biosciences Ribosome assembly in eukaryotic cells Website [email protected] Phone: 512-475-6350 Office Location NMS 1.126 Postal Address 2506 SPEEDWAY AUSTIN, TX 78712 Bio Publications Research Areas Centers Research in Arlen Johnson's Lab life hacks for flea\u0027s on mattress