WebE2F is a group of genes that encodes a family of transcription factors (TF) in higher eukaryotes.Three of them are activators: E2F1, 2 and E2F3a. Six others act as suppressors: E2F3b, E2F4-8. All of them are involved in the cell cycle regulation and synthesis of DNA in mammalian cells. E2Fs as TFs bind to the TTTCCCGC (or slight variations of this … WebApr 18, 2005 · The E2 factor (E2F) family of transcription factors are downstream targets of the retinoblastoma protein. ... 2000) and in several different plant species (Ramirez-Parra et al., 1999; Sekine et al ...
Atypical E2Fs: new players in the E2F transcription factor family
WebAug 18, 2006 · The E2F and DP proteins interact to form active transcription factors that bind to different gene promoters and regulate the expression of genes required for cell cycle progression. The RB protein, known as RB-related (RBR) in plants, binds to E2F proteins, masking the transactivation region and blocking transcriptional activity. WebTo elucidate the epigenetic maintenance mechanism for functional plant centromeres, we studied transcriptional regulation of the centromere-specific histone H3 variant CENH3 in Arabidopsis thaliana. We focused on the structure and activity of the CENH3 promoter (CENH3pro) and its regulation by E2F transcription factors.Use of CENH3pro::GUS … province of nb facebook
A hierarchical transcriptional network activates specific CDK
WebAs major regulators of the cell cycle, apoptosis and differentiation, E2F transcription factors have been studied extensively in a broad range of organisms. The recent identification of atypical E2F family members further expands our structural, functional and molecular view of the cellular E2F activity. Unlike other family members, atypical E2Fs … WebNov 15, 2024 · Recent studies have shown that a variety of cytokines are involved in cell cycle regulation and that the E2F-DP transcription factor (TF) family is one of the … WebThe onset of cell cycle in mammalian systems is primarily controlled by E2F-like transcription factors. Recent evidence shows that plant E2F homologs and their associated proteins likely play similar roles in higher plant development. We studied the function of plant E2F in gene regulation and morphogenesis using transgenic … province of nb youtube