WebFeb 1, 2024 · In one study, a sciATAC-seq (single-cell combinatorial indexed ATAC-seq) assay was used in a combinatorial tagging strategy ( Cusanovich et al., 2015 ). Here, thousands of nuclei were first separated into a 96-well plate in which ATAC-seq was performed with barcoded transposase complexes.

ChromSCape : a Shiny/R application for interactive analysis

Web(Buenrostro et al., 2015; Cusanovich et al., 2015). Together, scRNA-seq and scATAC-seq offer unprecedented resolution to reveal complex epigenetic events underlying tumor biology and give potential for the discovery of pathways governing tumorigenesis going beyond the standard taxonomic identifica-tion of cell types. WebNov 3, 2015 · Genome-Wide Association Studies of the Human Gut Microbiota The bacterial composition of the human fecal microbiome is influenced by many lifestyle factors, notably diet. It is less clear, however, what role host genetics plays in dictating the composition of bacteria living in the gut. first gold hops

Multiplex single cell profiling of chromatin accessibility by ... - PubMed

WebJun 30, 2015 · Cusanovich, D.A. et al. Science 348 , 910–914 (2015). The accessibility of chromatin to regulatory proteins provides an important layer of gene expression control, … WebAug 2, 2024 · With ~3.9 billion read pairs, we identified 104,039 cells, with ~12% of these being likely doublets or ‘collisions’ ( Cusanovich et al., 2015 ). The total number of cells profiled per tissue (after further filtering detailed below) ranged from 2,278 for cerebellum to 9,996 for lung ( Fig. 1C ). WebAug 21, 2015 · Overall Cusanovich et al. obtained scATAC-seq data from over 15,000 individual cells from mixtures of GM12878 lymphoblastoid cells with HEK293, HL-60, or … first golden state stimulus check